PPARG and aneurysm: Previous analysis demonstrated that PPARγ expression was increased in aneurysms of Marfan aortas with pathological cystic medial degeneration, and the severity of cystic medial degeneration and aortic diameter were positively correlated with the degree of PPARγ expression suggesting that increased expression of vascular smooth muscle PPARγ may contribute to the pathogenesis and progression of cystic medial degeneration [45].