ABCB1 and ovarian neoplasm: Interestingly, NCI/ADR-RES ovarian tumor cell line, expressing high levels of MDR1 and P-glycoprotein, which are related to multidrug resistance [55, 56], showed best TGI values (26.40 μg/mL), whereas doxorubicin showed almost no effect at concentrations of 25 μg/mL.