Serum CA-125 levels were significantly higher in patients with abnormal hepatic function (N = 65, 307.7 ± 444.7 U/mL) and low ALB levels (N = 66, 285.0 ± 303.0 U/mL) and those with ascites (N = 135, 242.7 ± 300.1 U/mL) compared to corresponding patients who had normal hepatic function (86.9 ± 174.2 U/mL) and normal serum ALB (97.7 ± 201.1 U/mL) or without ascites (20.7 ± 12.3 U/mL) (P < 0.05). This evidence concerns the gene ALB and Ascites.