Our results demonstrate co-incubation of FKBP12 with G295S also results in accumulation of amorphous aggregates and reduced ThT fluorescence intensity (lower panel in Fig. 5 and Supplementary Fig. 7), hinting on the potential role of FKBP12 to shift the aggregation process of amyloid-prone protein to form benign aggregates in different neurodegenerative diseases. Here, FKBP1A is linked to neurodegenerative disease.