FHIT and renal cell carcinoma: Chromosomal translocation at t(3;8)(p14.2;q24) was first described in hereditary RCC and a common region of loss in chromosome 3 was found in sporadic ccRCC [61–64]. FHIT gene has been identified at this locus in several other malignancies including lung, breast, cervical, gastric, and bladder cancers [65–69].