In order to characterize the expression of PHTF1 in primary T-ALL samples, we detected the expression level of PHTF1 in peripheral blood mononuclear cells (PBMCs) from 9 cases with T-ALL (median: 2.73 %, mean rank: 20.33, P = 0.004), as well as 13 cases with B-ALL (median: 3.34 %, mean rank: 21.54, P < 0.001). This evidence concerns the gene PHTF1 and acute lymphoblastic leukemia.