TNF and steatosis: The hepatic changes induced by the consumption of HFDE in both mouse strains are summarized in Table 2: (i) development of hepatomegaly was similar in both mouse strains; (ii) B6 accumulated more TG and cholesterol in the liver than A/J; (iii) circulating leukocytes are present in higher counting in A/J mice blood when compared to B6; (iv) liver proinflammatory environment involved in steatosis is different in B6 and A/J: HFDE-fed B6 mice produce higher levels of liver IL-12p70 while HFDE-fed A/J mice release more liver TNF-α cytokine.