A high KL–6 level, anti-MDA5 Ab positivity, high serum levels of ferritin, IL–6, IL–10, and IL–8, and a high level of AaDO2 have been reported as serological factors in DM-IP that indicate a poor prognosis [33–35, 36–39]. The gene discussed is CXCL8; the disease is incontinentia pigmenti.