As CXCL10 is also upregulated in other diseases associated with neuronal injury, such as diabetic retinopathy and stroke,57, 58 our study warrants further investigation of the CXCL10/CXCR3 axis in these diseases to determine whether or not this pathway has a general role in inducing inflammation and neuronal death and therefore targeting this pathway could be beneficial in a variety of diseases. The gene discussed is CXCR3; the disease is stroke disorder.