In polycystic kidneys, increased apoptosis is a key feature of the cyst epithelium and highly correlates with the degree of cyst formation.24 ANO6 could be detected in human cyst-lining cells and—in line with the in vitro data—colocalized with the ciliary marker acetylated tubulin (Figures 7a–d). The gene discussed is ANO6; the disease is polycystic kidney disease.