We explored genes related to the IL-4 and IL-10 cytokines; Figs 7–10 illustrates differences in expression between normal germinal centre (GC) B-cells (defined as centrocytes (CC) and centroblasts (CB)) and non-GC subtypes (naïve (N), plasmablasts (PB), memory (M) B-cells) and DLBCL cells using Bonferroni corrected p-values. The gene discussed is IL4; the disease is diffuse large B-cell lymphoma.