IL10RB and B-cell chronic lymphocytic leukemia: We found a up regulation of the IL10 and the IL10RB gene in DLBCL cells when compared to normal GC B-cell subpopulations supporting the hypothesis that this cytokine/receptor could play a role for the survival of germinal centre derived lymphomas, as supported by the earlier findings in CLL [56] and further supporting the protective effect of the low producer IL10 (rs1800872) AA genotype as well as the protective effect of the IL10RB (rs1058867) G allele [10,12].