LCN2 and acute kidney injury: In this study, patients with urinary tract infections also exhibited significantly increased calprotectin levels.24 They also conducted a second investigation on 87 patients (38 with AKI, 24 with prerenal AKI, and 25 healthy controls) and reported that urinary calprotectin exhibited an AUROC of 0.99, where as NGAL exhibited an AUROC of 0.82 with cut-off values of 440 and 52 ng/mL, respectively.