Although age, coma scale scores, severe CHF, AMI, and SCr, albumin, hemoglobin, BNP, CKD, urinary NGAL, and calprotectin levels were associated with AKI according to the univariate analysis, only SCr, hemoglobin, and calprotectin levels were independently associated with intrinsic AKI according to the multivariate analysis (Table 4). The gene discussed is NPPB; the disease is congestive heart failure.