However, our findings regarding Capn6 expression regulation were contradictory to a study by Tonami et al. [100] reporting that Capn6 was a suppressor of skeletal muscle differentiation, and a study by Liu et al. [101] indicating that Capn6 promoted cancer cell proliferation and was positively regulated by the PI3K-Akt signaling pathway. The gene discussed is AKT1; the disease is cancer.