Compared with the HPDE6 cells, all PC cell lines had higher HOTTIP-005, XLOC_006390, and RP11-567G11.1 expression; HOTTIP-005, XLOC_006390, and RP11-567G11.1 expression was highest in the AsPC-1, SW1990, and PANC-1 cells, respectively (Figure 3A). This evidence concerns the gene HOTTIP and pachyonychia congenita.