MMP9 and lung large cell carcinoma: The report from Hou et al [22], showed that expression of EGFR, MMP9 and TGFβ-1 were all upregulated in human lung cancer samples, including LCL (large cell lung cancer), ADC (adenocarcinoma) and SCC (squamous cell carcinoma), compared to adjacent normal tissues (N) (Figure 8D–8F).