As shown by immunohistochemical analyses, ganciclovir did not reduce numbers of proliferating microglia (Iba1+/Ki67+) and total numbers of microglia (Iba1+) neither during TMEV (Fig. 1E,F), nor during cuprizone induced demyelination and the subsequent remyelination (Fig. 2B,C), nor during VSV induced encephalitis (Fig. 3B,C). This evidence concerns the gene MKI67 and encephalitis.