During the long-term follow up (≥1 year), the cardiovascular outcomes in insulin-treated DM patients were still significantly higher: All-cause mortality (OR 1.69, 95 % CI 1.44–1.98, p < 0.00001), MI (OR 1.49, 95 % CI 1.21–1.83, p = 0.0001), TLR (OR 1.36, 95 % CI 1.17–1.58, p < 0.0001), MACEs (OR 1.53, 95 % CI 1.28–1.82, p < 0.00001) and, Stent thrombosis (OR 1.59, 95 % CI 1.21–2.10, p = 0.001) compared to non-insulin treated DM patients after PCI. The gene discussed is INS; the disease is diabetes mellitus.