In this 14-equation SDMM, variables P, Mkf, Mkb, T, NR, Nf, Nb, r1, D, MR, Mf, Mb, H, and CA represent levels of pathogen, free Kupffer Cell, bound Kupffer Cell, TNF-α, resting neutrophil, free activated neutrophil, bound activated neutrophil, rate of resting neutrophil activated under infection, damaged tissue, resting monocyte, free activated monocytes, bound activated monocytes, HMGB-1, and IL-10, respectively. Here, HMGB1 is linked to infection.