Several secreted or intracellular factors related to cell regulation (“signaling pathway”) were also upregulated, some of them (Trib3, CTGF/CCN2, Egr1, Stat3...) having been linked to inflammation, tissue repair, liver fibrosis and TGFβ signaling [27, 28]. The gene discussed is TGFB1; the disease is Hepatic fibrosis.