GATA1 and Diamond-Blackfan anemia: Although it is unclear whether GATA1 mutations define a distinct subset of DBA or it is somehow related to ribosomal dysfunction, a recent study published by Ludwig et al. confirmed the decreased GATA1 mRNA translation in hematopoietic cells from patients with ribosomal haploinsufficiency, suggesting an impairment of selective GATA1 translation initiation from reduction of ribosomal protein as the potential pathogenesis in this subset of DBA [49].