Of the 21 HE genes associated with “Hepatic Fibrosis”, 17 HE genes are expressed higher in abdominal fat of the LL chickens, including 5 collagen genes (COL3A-COL6A), fibronectin 1 (FN1), spondin 1 and 2 (SPON1, SPON2), fibrillin 1 (FBN1), transforming growth factor, beta receptor II (TGFBR2) and thrombospondin 1 (THBS1). The gene discussed is SPON2; the disease is Hepatic fibrosis.