For incident storage LUTS, removing CRP from the final model produced a moderate decrease in the multi-adjusted effect size of depression (Model 1: 1.26 (1.01, 4.02) to Model 2: 1.18 (0.96, 3.4) and model fit (R2change: 0.253–0.221) (Table 2). This evidence concerns the gene CRP and depressive symptom measurement.