According to the ADC clinical-genomic profile, patients with a higher risk of death showed an increase in the copy number of YES1, TYMS, MYO1E, SLC25A20 and PSMA4, and a decrease in the copy number of HMGN1 and POFUT2. YES1 is a non-receptor tyrosine kinase from the SRC family kinase proteins. The gene discussed is MYO1E; the disease is AIDS dementia complex.