SNAI1 and esophageal squamous cell carcinoma: Given that the induction of EMT by ectopic expression of either the Twist or Snail transcription factors generated stem cell-like cells [32], we proposed that SLC39A6 might regulate the stemness of esophageal cancer and promote the invasion of ESCC cells by affecting the expression of STAT3 and Snail, which needs further exploration.