SGCB and hereditary elliptocytosis: mRNA expression levels of transcripts for sGCα1, sGCα2 and sGCβ1 protein were similar in the brain, the kidney, the lung and the left ventricle of apo-sGC (KI), HE, and WT mice (Fig. 1a), indicating that introduction of the H105F mutation in sGCβ1 does not affect expression of sGC subunits.