To investigate whether it is possible to mount immune responses toward the above mentioned cancer antigens, we immunized 12 healthy outbred pigs holding the swine leukocyte antigen (SLA)-1*04:01, SLA-3*04:01, SLA-1*07:02, and/or SLA-2*05:02 MHC class I alleles with 20mer overlapping peptides spanning the entire sequence of IDO and RhoC. Here, IDO1 is linked to cancer.