CD4 and HIV infectious disease: In order to test the ability of NK cells stimulated by S100A9 proteins and primed by DCs to control HIV infection in CD4+ T cells, NK cells were pre-stimulated by S100A9 proteins and cultured during 4 days with DCs infected or not by MVAWT or MVAHIV, then NK cells were collected and incubated with HIV-infected CD4+ T cells, and after 10 days the percentage of HIV p24+ CD4+ T cells in the culture was measured (Figure 4B).