However, as all S100A9-tetramer-stimulated NK cells had a similar level of activation and NKG2C expression at the end of the priming, and as NK cells stimulated by S100A9 tetramers and primed by MVAHIV-infected DCs displayed the highest ability to control HIV infection in CD4+ T cells, we speculate that additional mechanisms other than NK-cell activation and NKG2C-triggering might be implicated. This evidence concerns the gene KLRC2 and HIV infectious disease.