Interestingly, we observed that pre-stimulation of NK cells by S100A9 tetramers, but not S100A9 monomers, resulted in significantly lower percentage of HIV p24+ CD4+ T cells in all priming conditions (Figure 4C), indicating higher ability of S100A9-tetramer-stimulated NK cells to control HIV infection. This evidence concerns the gene S100A9 and HIV infectious disease.