Conversely, IL15 has anti-apoptotic and neurotrophic effects, due to its ability to suppress nitric oxide in neurons (Budagian et al., 2006), which can be one of the components responsible for its protective effects in experimental autoimmune encephalomyelitis (Gomez-Nicola et al., 2010a). Here, IL15 is linked to experimental autoimmune encephalomyelitis.