The extent of A-to-I RNA editing in BC was investigated by paired exome and transcriptome sequencing of a broad series of BC samples representing the principal intrinsic subtypes including 17 triple-negative (TN), 14 HER2-positive (HER2), 16 luminal A (LA), and 11 luminal B (LB) tumors (Table S1). This evidence concerns the gene ERBB2 and breast cancer.