Furthermore, Vpu depletes SNAT1 from activated primary human CD4+ T cells both in the context of viral infection (Figures S4D and S4E) and as a single gene in transduced cells purified by Antibody-Free Magnetic Cell Sorting (AFMACS; Figures 3G, panel 5, 3H, lane 5, and S4F) (Matheson et al., 2014). Here, CD4 is linked to viral infectious disease.