The identified genomic rearrangements affected genic areas of a number of known cancer driver genes, e.g., TP53, ERBB2, EZH2, ATM, RB1, and PTEN but a large number of affected genes were not previously associated with cancer (not found in COSMIC) and further studies are needed to explore whether these could constitute new cancer-associated genes. This evidence concerns the gene EZH2 and cancer.