Of 27 KLF14-KO mice studied, 2 (7.4%) developed lung adenomas, 4 (14.8%) developed lymphoma in the spleens and 3 (11.1%) developed lymphoma in the lymph nodes (Fig. 1f), whereas no spontaneous tumour was identified in other organs such as the heart, liver, kidney, breast, colon and thymus. Here, KLF14 is linked to neoplasm.