Despite this, Serinc1 and Slc16a10, although not directly attributed in the literature with immune-related roles, have functions that could be postulated to affect immune cell responses and/or β-cell activity, which could be revealed in the context of the “sensitized” NOD genetic background (i.e., the NOD mouse strain enables detection of mutated genes that increase or decrease diabetes incidence). The gene discussed is SLC16A10; the disease is diabetes mellitus.