CDH3 and neoplasm: In contrast to the models presented above, aberrant expression of P-cadherin associated with aggressive tumour behaviour is observed in breast [53], gastric [54], endometrial [55, 56], ovarian [57], prostate [42], pancreatic [58], bladder [41] and colorectal carcinomas [9], as well as in basocellular and squamous carcinomas of the skin [59].