CD177 and cancer: Autophagy is widely involved in many physiological process, such as cell survival, embryo development, longevity, clearance of toxic aggregate-prone proteins, cell surface receptor trafficking and protection of host from pathogen infection.[19, 38–40] Dysregulation of autophagy contributes to a number of diseases including tumorigenesis.[17, 19] However, the role of autophagy in cancer is still controversial.