At bivariate analysis, increasing age,, prior history of a stroke, hours spent outdoors, increasing albumin and HDLC concentrations had p values ≤ 0.1 and were entered into the multivariate analysis model, Gender, diabetes mellitus, obesity, and a history of hypertension were also included as important confounders (Table 2). The gene discussed is ALB; the disease is obesity due to melanocortin 4 receptor deficiency.