A decrease of VEGF plasma levels resulted from the interaction of rs1800779 with obesity and triglycerides (β = −0.11, P = 0.018, β = −0.04, P = 0.043 respectively), while its interaction with HDL-C was associated with an increase in VEGF plasma levels (β = 0.12, P = 0.005). The gene discussed is VEGFA; the disease is obesity disorder.