AKR1C1 and neoplasm: Several other genes were also upregulated in the presence of NFE2L2 aberrations, for example, NQO1, TXNRD1, PRDX1, GSR, GPX2, GCLM, FTL, AKR1C1, TXN, SQSTM1, GSTA1, KEAP1, GSTA4, ABCC1, and GCLC were upregulated in six to three tumour types (Supplementary Data 7).