Breast cancer-related variants – BRCA1 (OMIM 113705), BRCA2 (OMIM 600185), and PALB2 (OMIM 610355 were present in four patients (16%); Lynch syndrome-related gene sequence alterations – MLH1 (OMIM 120436), MSH2 (OMIM 609309), MSH6 (OMIM 600678), PMS2 (OMIM 600259), and PMS1 (OMIM 600258 were detected in six patients (24%). The gene discussed is PALB2; the disease is Lynch syndrome.