Compared with HCs, the pSS patients showed a significant increase of circulating CD4+CD25+CD161+ T cell subset (13.04 ± 7.32 versus 4.60 ± 1.05, p < 0.0001, Figure 3(d)), while the levels of CD4+CD25−CD161+ T and the overall CD4+CD161+ T in PBMCs were not significantly different between the pSS patients and HCs (both p > 0.05, Figures 3(e) and 3(f)). The gene discussed is KLRB1; the disease is peeling skin syndrome.