Kasabach-Merritt phenomenon is characterized by vascular tumour and consumptive coagulopathy with life-threatening thrombocytopenia, prolonged prothrombin time (PT), and activated partial thromboplastin time (aPTT), hypofibrinogenemia, and the presence of D-dimer and fibrin split products [2]. The gene discussed is F2; the disease is Thrombocytopenia.