BCR and myeloproliferative neoplasm: Chronic myeloid leukemia (CML) is a myeloproliferative neoplasm caused by the BCR-ABL1, a chimeric gene generated as a result of a reciprocal translocation [t(9;22)(q34;q11)], cytogenetically visible as the Philadelphia chromosome (Ph) that places sequences from the ABL gene from chromosome 9 downstream of the BCR gene on chromosome 22 [1, 2].