TNF and rheumatoid arthritis: Of the 17 Th1/Th2/Th17-related cytokines, TNF-α, IL-1β, IL-2, IL-4, IL-6, IL-7, IL-10, IL-12, GM-CSF, IFN-γ, and MCP-1 in the blood of RA patients were positively correlated with the DAS28 disease activity score (Table 3).