Next we examined p-IKKα/β expression by immunochemical staining of paraffin-embedded sections of 24 prostate cancer specimens consisting of 14 low-grade tumor (Gleason score 5–6), 10 median-grade tumor (Gleason score 7–8) and 6 benign tissues (Figure 1C). The gene discussed is CHUK; the disease is Familial prostate cancer.