Although LY294002 and 15e (a PI3K inhibitor potently inhibits p100α activity) blocked AKT phosphorylation in most ABC subtype of DLBCL cells, both treatment had minimal effects on the growth, division, and apoptosis of OCI-Ly10 and some other ABC DLBCL cells except for HBL-1 and TMD8 cells [8]. Here, AKT1 is linked to aneurysmal bone cyst.