CD4 and HIV infectious disease: Assuming optimal levels of engagement throughout the care continuum (i.e. from diagnosis to virological suppression), we project 831,000 new HIV infections (95% UR 561,000–1,447,000) and 482,000 AIDS-related deaths (95% UR 427,000–821,000) would occur in India over 20 years if current ART initiation practices (CD4 ≤350 cells/mm3) were maintained (Table 2).