To further investigate this hypothesis and to further explore whether DLB pathology affects CSF IL-6 levels differently compared with AD pathology, we here compared IL-6 CSF concentrations in patients with DLB, patients with AD and control subjects without dementia and examined the potential association between the IL-6 levels and biomarkers correlating with neuropathological changes characteristic of AD and DLB. The gene discussed is IL6; the disease is Lewy body dementia.