Staining with this antibody revealed that PAT4 was localised to an asymmetric perinuclear region in formalin-fixed, paraffin-embedded 786-O renal cancer cells, which express high PAT4 levels, and lost in 786-O cells transfected with PAT4 small interfering RNA (siRNA) (Figures 1a and b). This evidence concerns the gene SLC36A4 and renal carcinoma.