Recently, we reported on the presence and abundance of suppressive PD-L1+CD14+ M2-macrophage-like cells, myeloid-derived suppressor cells (MDSCs), T cells expressing co-inhibitory molecules (PD-1 and CTLA-4), and regulatory T cells (Tregs) in tumor-positive lymph nodes (LN+) compared to tumor-negative lymph nodes (LN−) from cervical cancer patients [7]. The gene discussed is CD274; the disease is cervical carcinoma.