Our results point to a strong immunosuppressive microenvironment in LN+ from patients with cervical cancer with high Treg levels, low CD8+ T cell/Treg ratio, and high levels of PD-L1+- and HLA-DR+ myeloid cells, which is consistent with previous data based from flowcytometric analyses [7, 9] and immunohistochemical stainings [2]. This evidence concerns the gene CD8A and cervical cancer.