In order to determine whether the MET currently in clinical trials for cancer treatment, can augment the cell proliferation inhibitory effects of TMZ in glioma cells and GSCs, glioma cells and GSCs (derived from U87 and U251 glioma cell lines) were plated with TMZ either alone or with MET, all cells were assessed using the CCK-8 assay. Here, MET is linked to glioma.